21:I[432972,["/_next/static/chunks/bb923814e1f4d2e9.js","/_next/static/chunks/dd3ee9f5b7716ca6.js","/_next/static/chunks/4204a0ae82542ca8.js","/_next/static/chunks/1270dead247da766.js","/_next/static/chunks/6e1aa89a642f40be.js","/_next/static/chunks/2d7aa753e81324a8.js","/_next/static/chunks/8ffd0b71567920d8.js","/_next/static/chunks/67ea6dfd21f16c5f.js","/_next/static/chunks/24eb4379f68013fd.js","/_next/static/chunks/b8cd775ffdf935bd.js","/_next/static/chunks/983103cd9eb7b428.js","/_next/static/chunks/263f2cdcb9aa2341.js","/_next/static/chunks/294b9525248c8e5f.js"],"default"] 22:T473,Diarrheal shellfish toxins (DSTs) are among the most widely distributed phytotoxins, and are associated with diarrheal shellfish poisoning (DSP) events in human beings all over the world. Therefore, it is urgent and necessary to identify an effective method for toxin removal in bivalves. In this paper, we found that curcumin (CUR), a phytopolylphenol pigment, can inhibit the accumulation of DSTs (okadaic acid-eq) in the digestive gland of Perna viridis after Prorocentrum lima exposure. qPCR results demonstrated that CUR inhibited the induction of DSTs on the aryl hydrocarbon receptor (AhR), hormone receptor 96 (HR96) and CYP3A4 mRNA, indicating that the CUR-induced reduction in DSTs may be correlated with the inhibition of transcriptional induction of AhR, HR96 and CYP3A4. The histological examination showed that P. lima cells caused severe damage to the digestive gland of P. viridis, and the addition of curcumin effectively alleviated the damage induced by P. lima. In conclusion, our findings provide a potential method for the effective removal of toxins from DST-contaminated shellfish.23:T53e,Zhang, D.S.; Pei, S.S.; Duan, G.F.; Feng, X.B.; Zhang, Y.B., and Wu, J., 2020. The pollution level, spatial and temporal distribution trend and risk assessment of heavy metals in Bohai Sea of China. In: Bai, X. and Zhou, H. (eds.), Advances in Water Resources, Environmental Protection, and Sustainable Development. Journal of Coastal Research, Special Issue No. 115, pp. 354-360. Coconut Creek (Florida), ISSN 0749-0208.In recent years, the rapid industrialization and urbanization of coastal areas have caused serious environmental pressure on the Bohai Sea. The investigator collected the concentration of 7 heavy metals (As, Cu, Cd, Cr, Hg, Pb, Zn) in the Bohai Sea from 2013 to 2017.The results showed that: The main pollution factor of heavy metals in the sea water quality of the study area was Pb. The concentration of Hg increased significantly with the increase of depth. Hg and Cd, due to their high toxicity factors, are the main potential ecological risk factors of surface sediments in the study area. The main heavy metal pollution factor in living creatures is Pb. River discharge, oil exploitation, port area activities and atmospheric subsidence are the main sources of Marine environmental pollution. This study provides ideas for predicting the content of another medium heavy metal in the environment based on one medium.

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1	Medicine	3	3	66
2	Engineering	2	2	34
3	Biology	2	2	52
4	Management	1	1	10
5	Social Sciences	1	1	14

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