R C May

Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes.

William E. Mitch, Ruth Medina, S Grieber et al. · Journal of Clinical Investigation · 1994 · 403 citations · Full text

Muscle Function, Proteasome, Metabolic Remodeling +20

Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism.

R C May, R A Kelly, William E. Mitch · Journal of Clinical Investigation · 1986 · 368 citations · Full text

Rat Muscle, Glucocorticoid, Oxidative Stress +23

Mechanisms for defects in muscle protein metabolism in rats with chronic uremia. Influence of metabolic acidosis.

R C May, R A Kelly, William E. Mitch · Journal of Clinical Investigation · 1987 · 322 citations · Full text

Metabolic Disorder, Muscle Protein Turnover, Oxidative Stress +22

Acidosis, not azotemia, stimulates branched-chain, amino acid catabolism in uremic rats

Yoko Hara, R C May, Ralph A. Kelly et al. · Kidney International · 1987 · 182 citations · Full text

Electrolyte Disorder, Uremic Rats, Biochemistry +9

Branched-chain amino acid metabolism in rat muscle: abnormal regulation in acidosis

R C May, Yasushi Hara, R A Kelly et al. · American Journal of Physiology-Endocrinology and Metabolism · 1987 · 141 citations

Rat Muscle, Muscle Function, Bcaa Metabolism +18