Michael I. Barton

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics

Michael I. Barton, Stuart A. MacGowan, Mikhail A. Kutuzov et al. · eLife · 2021 · 374 citations · Full text

A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity

Chang Liu, Daming Zhou, Aiste Dijokaite-Guraliuc et al. · Cell Reports Medicine · 2024 · 27 citations · Full text

Humoral Response, Immunology, Less Immune Evasion +19

Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors

Ashna Patel, Violaine André, Sofı́a Bustamante Eguiguren et al. · The EMBO Journal · 2023 · 20 citations · Full text

Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants

Stuart A. MacGowan, Michael I. Barton, Mikhail A. Kutuzov et al. · PLoS Computational Biology · 2022 · 15 citations · Full text

A generic cell surface ligand system for studying cell–cell recognition

Eleanor M Denham, Michael I. Barton, Susannah Black et al. · PLoS Biology · 2019 · 13 citations · Full text