Susan Tantawi

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis

Nikhil Hirani, Alison C. MacKinnon, Lisa Nicol et al. · European Respiratory Journal · 2020 · 219 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade

Lynda Vuong, Eleni Kouverianou, Claire Rooney et al. · Cancer Research · 2019 · 141 citations · Full text

Medicine, Immunology, Oncology +16

Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease

Fredrik R. Zetterberg, Alison C. MacKinnon, Thomas Brimert et al. · Journal of Medicinal Chemistry · 2022 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants

Vassilios Aslanis, Robert J. Slack, Alison C. MacKinnon et al. · Cancer Chemotherapy and Pharmacology · 2023 · 40 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +9