Long-Term Treatment with Lithium Alleviates Memory Deficits and Reduces Amyloid-β Production in an Aged Alzheimer's Disease Transgenic Mouse Model

Xin Zhang, Xin Heng, Ting Li, +6

Journal of Alzheimer s Disease

MitophagyAgingAutophagy ActivityProlonged Lithium TreatmentChronic Lithium Treatment +14

An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity

Yunlan Du, Dehua Yang, Li Liang, +7

Autophagy

Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer’s disease neuropathology in APPSwe/PS1A246E transgenic mice

Xin Zhang, Lixi Li, Xiaojie Zhang, +7

Neurobiology of Aging

Knockout MouseNeurodegenerative DiseasesAlzheimer's DiseaseNeurobiology Of DiseaseDevelopmental Biology +11

D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone‐induced apoptosis through inhibition of caspase‐ and JNK‐dependent pathways

Sheng Chen, Xiaojie Zhang, Dehua Yang, +4

FEBS Letters

Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response

Yunlan Du, Fei Wang, Jing Zou, +6

Neurobiology of Aging

Neurodegenerative DiseasesMitophagyMolecular NeuroscienceHeat Shock ResponseMedicine +8

Multiple Molecular Pathways Are Involved in the Neuroprotection of GDNF Against Proteasome Inhibitor Induced Dopamine Neuron Degeneration In Vivo

Yunlan Du, Dehua Yang, Xiaojie Zhang, +2

Experimental Biology and Medicine

Proteasome Inhibitor LactacystinNeurodegenerative DiseasesMedicineNeuropharmacologyNeurochemical Biomarkers +10

HDAC6-mediated Hsp90 deacetylation reduces aggregation and toxicity of the protein alpha-synuclein by regulating chaperone-mediated autophagy

Yunlan Du, Xiao Min Yang, Zezhi Li, +5

Neurochemistry International

Cell AutophagyMitophagyProtein FunctionAutophagyChaperone-mediated Autophagy +7

Allelic distributions of CYP2D6 gene copy number variation in the Eastern Han Chinese population

Haihui Sheng, Aiping Zeng, Wenxiang Zhu, +9

Acta Pharmacologica Sinica

BiologyAllelic VariantHaplotype DeterminationAllelic DistributionsGenetics +7

c-Jun N-Terminal Kinase Mediates Lactacystin-Induced Dopamine Neuron Degeneration

Xuping Li, Yunlan Du, Xiaolan Fan, +3

Journal of Neuropathology & Experimental Neurology

MitophagyApoptosisCell DeathSocial SciencesOxidative Stress +16

Adeno-Associated Virus Type 2 Vector-Mediated Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Induces Neuroprotection and Neuroregeneration in a Ubiquitin-Proteasome System Impairment Animal Model of Parkinson’s Disease

Yunlan Du, Xiaojie Zhang, Qingqing Tao, +2

Neurodegenerative Diseases