Hitoshi Doihara

TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells

Katsura Nozawa, Eri Kawabata-Shoda, Hitoshi Doihara et al. · Proceedings of the National Academy of Sciences · 2009 · 397 citations · Full text

QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells

Hitoshi Doihara, Katsura Nozawa, Ryosuke Kojima et al. · Molecular and Cellular Biochemistry · 2009 · 70 citations

Trpa1 Activation, Qgp-1 Cells, Signal Transduction +10

Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain

Ryosuke Kojima, Katsura Nozawa, Hitoshi Doihara et al. · European Journal of Pharmacology · 2013 · 64 citations

Molecular Pharmacology, Visceral Pain, Health Sciences +10

A novel glycine transporter-1 (GlyT1) inhibitor, ASP2535 (4-[3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole), improves cognition in animal models of cognitive impairment in schizophrenia and Alzheimer's disease

Katsuya Harada, Kazuhiro Nakato, Junko Yarimizu et al. · European Journal of Pharmacology · 2012 · 60 citations

Alzheimer's Disease, Medicine, Cognitive Dysfunction +12

TRPA1 agonists delay gastric emptying in rats through serotonergic pathways

Hitoshi Doihara, Katsura Nozawa, Eri Kawabata-Shoda et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2009 · 58 citations

Molecular Pharmacology, Gastrointestinal Pharmacology, Medicine +6