Tyler B. Hughes

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio et al. · PLoS Pathogens · 2016 · 441 citations · Full text

Drug Target, Bioorganic Chemistry, Antiparasitic Agent +17

Modeling Epoxidation of Drug-like Molecules with a Deep Machine Learning Network

Tyler B. Hughes, Grover P. Miller, S. Joshua Swamidass · ACS Central Science · 2015 · 194 citations · Full text

Modeling Reactivity to Biological Macromolecules with a Deep Multitask Network

Tyler B. Hughes, Na Le Dang, Grover P. Miller et al. · ACS Central Science · 2016 · 103 citations · Full text

Site of Reactivity Models Predict Molecular Reactivity of Diverse Chemicals with Glutathione

Tyler B. Hughes, Grover P. Miller, S. Joshua Swamidass · Chemical Research in Toxicology · 2015 · 98 citations

Drug Target, Bioorganic Chemistry, Chemical Analysis +22

XenoSite server: a web-available site of metabolism prediction tool

Matthew K. Matlock, Tyler B. Hughes, S. Joshua Swamidass · Bioinformatics · 2014 · 91 citations · Full text