Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

Tommi Vatanen, Aleksandar D. Kostic, Eva d’Hennezel, +21

Cell

DysbiosisAutoimmune DiseaseMicrobial PathogensAllergyMucosal Immunology +8

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

Aleksandar D. Kostic, Dirk Gevers, Heli Siljander, +19

Cell Host & Microbe

Type 1DysbiosisMicrobiotaGut MicrobiologyHuman Microbial Flora +6

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

Guoyan Zhao, Tommi Vatanen, Lindsay Droit, +14

Proceedings of the National Academy of Sciences

AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

Steffen Meyer, Martin J. Woodward, Christina Hertel, +24

Cell

Increased Blood Levels of Growth Factors, Proinflammatory Cytokines, and Th17 Cytokines in Patients with Newly Diagnosed Type 1 Diabetes

Kristi Alnek, Kalle Kisand, Kaire Heilman, +3

PLoS ONE

ImmunodeficienciesImmunologyImmune RegulationPathologyCd4 T Cell Responses +22

Th1/Th17 Plasticity Is a Marker of Advanced β Cell Autoimmunity and Impaired Glucose Tolerance in Humans

Linnea Reinert‐Hartwall, Jarno Honkanen, Harri M. Salo, +10

The Journal of Immunology

Early Detection of Peripheral Blood Cell Signature in Children Developing β-Cell Autoimmunity at a Young Age

Henna Kallionpää, Juhi Somani, Soile Tuomela, +18

Diabetes

Early childhood infections precede development of beta-cell autoimmunity and type 1 diabetes in children with HLA-conferred disease risk

Neea Mustonen, Heli Siljander, Aleksandr Peet, +5

Pediatric Diabetes

Maturation of Gut Microbiota and Circulating Regulatory T Cells and Development of IgE Sensitization in Early Life

Terhi Ruohtula, Marcus C. de Goffau, Janne Nieminen, +11

Frontiers in Immunology

Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins

Dmytro Fishman, Kai Kisand, Christina Hertel, +18

Frontiers in Immunology