Ligia A. Papale

Altered Function of the SCN1A Voltage-gated Sodium Channel Leads to γ-Aminobutyric Acid-ergic (GABAergic) Interneuron Abnormalities

Melinda S. Martin, Karoni Dutt, Ligia A. Papale et al. · Journal of Biological Chemistry · 2010 · 231 citations · Full text

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy

M. S. Martin, Beisha Tang, Ligia A. Papale et al. · Human Molecular Genetics · 2007 · 205 citations · Full text

Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice

Ligia A. Papale, Barbara Beyer, Julie Miller Jones et al. · Human Molecular Genetics · 2009 · 127 citations · Full text

Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility

Stacey B. B. Dutton, Christopher D. Makinson, Ligia A. Papale et al. · Neurobiology of Disease · 2012 · 126 citations · Full text

Seizure Susceptibility, Neurobiology Of Disease, Neurophysiology +8

A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation

Bin Tang, Karoni Dutt, Ligia A. Papale et al. · Neurobiology of Disease · 2009 · 96 citations · Full text

Generalized Epilepsy, Synaptic Plasticity, Molecular Neuroscience +12