Ryota Shiraki

Discovery of Ipragliflozin (ASP1941): A novel C-glucoside with benzothiophene structure as a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus

Masakazu Imamura, Keita Nakanishi, Takayuki Suzuki et al. · Bioorganic & Medicinal Chemistry · 2012 · 130 citations · Full text

Medicinal Chemistry, Biochemistry, Benzothiophene Structure +10

Total Synthesis of Natural PI-091, a New Platelet Aggregation Inhibitor of Microbial Origin

Ryota Shiraki, Akihiko Sumino, Kin‐ichi Tadano et al. · The Journal of Organic Chemistry · 1996 · 83 citations

Bioorganic Chemistry, Organic Chemistry, Medicinal Chemistry +16

Total Syntheses of Natural Pseurotins A, F2, and Azaspirene

Shinya Aoki, Takahiro Oi, Kazuya Shimizu et al. · Bulletin of the Chemical Society of Japan · 2004 · 38 citations

Diversity Oriented Synthesis, Derivatives, Biochemistry +13

Nickel-Catalyzed Addition of C–C Bonds of Amides to Strained Alkenes: The 1,2-Carboaminocarbonylation Reaction

Yuri Ito, Syun Nakatani, Ryota Shiraki et al. · Journal of the American Chemical Society · 2022 · 37 citations

Cross-coupling Reaction, Nickel-catalyzed Addition, Engineering +10

Total Synthesis of PI-091

Ryota Shiraki · Tetrahedron Letters · 1995 · 35 citations

Combinatorial Chemistry, Total Synthesis, Organic Chemistry +3