Effective GDNF brain delivery using microspheres—A promising strategy for Parkinson's disease

Elisa Garbayo, Claudia N. Montero‐Menei, Eduardo Ansorena, +3

Journal of Controlled Release

NanoparticlesNanomedicineNeurodegenerative DiseasesNanotherapeuticsEngineering +8

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells

Eduardo Ansorena, Elena R. García–Trevijano, Maria Luz Martínez‐Chantar, +6

Hepatology

Lipid PeroxidationApoptosisPathologyCell DeathCultured Rat Hepatocytes +20

Injectable alginate hydrogel loaded with GDNF promotes functional recovery in a hemisection model of spinal cord injury

Eduardo Ansorena, Pauline De Berdt, Bernard Učakar, +8

International Journal of Pharmaceutics

Role of reactive oxygen species, glutathione and NF-κB in apoptosis induced by 3,4-methylenedioxymethamphetamine (“Ecstasy”) on hepatic stellate cells

Cristina Montiel‐Duarte, Eduardo Ansorena, María J. López‐Zabalza, +2

Biochemical Pharmacology

Reactive Oxygen SpeciesBiochemistryHepatic Stellate CellsMedicineLiver Physiology +12

Brain delivery of microencapsulated GDNF induces functional and structural recovery in parkinsonian monkeys

Elisa Garbayo, Eduardo Ansorena, Hugo Lana, +5

Biomaterials

Structural RecoveryNeuroregenerationNeuropharmacologyNeuroprotectionNeuroscience +7

Vascular endothelial growth factor‐loaded injectable hydrogel enhances plasticity in the injured spinal cord

Anne des Rieux, Pauline De Berdt, Eduardo Ansorena, +13

Journal of Biomedical Materials Research Part A

Tissue EngineeringEngineeringBiomaterials DesignVascular Endothelial GrowthBiofabrication +18

Sustained release of bioactive glycosylated glial cell-line derived neurotrophic factor from biodegradable polymeric microspheres

Elisa Garbayo, Eduardo Ansorena, José L. Lanciego, +2

European Journal of Pharmaceutics and Biopharmaceutics

Tissue EngineeringSustained ReleaseGlial Cell-lineEngineeringGlycobiology +6

Long‐term neuroprotection and neurorestoration by glial cell‐derived neurotrophic factor microspheres for the treatment of Parkinson's disease

Elisa Garbayo, Eduardo Ansorena, José L. Lanciego, +2

Movement Disorders

Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway

Marina Ruiz de Galarreta, Amaia Navarro, Eduardo Ansorena, +5

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

FibrosisSignal TransductionMolecular PhysiologySystems BiologyBrefeldin A +13

NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells

Aitor Andueza, Naiara Garde, Antonia García-Garzón, +5

Free Radical Biology and Medicine

FibrosisHepatologyBiochemistryLiver PhysiologyCell Death +10