Freek J. Janssen

Development of an Activity‐Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase‐α in Brain

Marc P. Baggelaar, Freek J. Janssen, Annelot C. M. van Esbroeck et al. · Angewandte Chemie International Edition · 2013 · 75 citations

Systems Pharmacology, Inhibitory Activity, Proteinlipid Interaction +15

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

Marc P. Baggelaar, Pascal Chameau, Vasudev Kantae et al. · Journal of the American Chemical Society · 2015 · 63 citations

Proteinlipid Interaction, Drug Target, Diacylglycerol Lipase +17

Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding

Hui Deng, Sander Kooijman, Adrianus M. C. H. van den Nieuwendijk et al. · Journal of Medicinal Chemistry · 2016 · 38 citations · Full text

Discovery of Glycine Sulfonamides as Dual Inhibitors of<i>sn</i>-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6

Freek J. Janssen, Hui Deng, Marc P. Baggelaar et al. · Journal of Medicinal Chemistry · 2014 · 33 citations · Full text

Proteinlipid Interaction, Peptide Science, Chemical Biology +18

A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

Tom van der Wel, Freek J. Janssen, Marc P. Baggelaar et al. · Journal of Lipid Research · 2015 · 30 citations · Full text