YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation

Shuai Wang, Feng Xie, Feng Chu, +11

Nature Immunology

Protein FunctionSignal TransductionViral ImmunityImmunologyAntiviral Response +9

Tumor-derived exosomes antagonize innate antiviral immunity

Liang Gao, Lin Wang, Tong Dai, +10

Nature Immunology

Tumor-derived ExosomesImmunologyTumor ImmunityAntiviral ResponseExtracellular Microvesicles +6

Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7

Zhengkui Zhang, Fan Yao, Feng Xie, +17

Nature Communications

Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling

Feng Xie, Xiaoxue Zhou, Peng Su, +14

Nature Communications

Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID‐19 Therapy

Feng Xie, Peng Su, Ting Pan, +10

Advanced Materials

ImmunologyViral PathogenesisExtracellular MicrovesiclesViral Structural ProteinCell Signaling +14

<scp>USP8</scp> promotes cancer progression and extracellular vesicle‐mediated <scp>CD8</scp> + T cell exhaustion by deubiquitinating the <scp>TGF</scp> ‐β receptor <scp>TβRII</scp>

Feng Xie, Xiaoxue Zhou, Heyu Li, +14

The EMBO Journal

microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress

Binghua Dai, Li Geng, Yue Wang, +5

Cell Death and Disease

Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair

Li Wan, Jinhua Han, Ting Liu, +4

Proceedings of the National Academy of Sciences

Protein AssemblyGeneticsRecq FamilyGenomic MechanismMolecular Biology +19

Investigation of serum lncRNA-uc003wbd and lncRNA-AF085935 expression profile in patients with hepatocellular carcinoma and HBV

Jiongjiong Lu, Feng Xie, Geng Li, +3

Tumor Biology

Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation

Zhen Yang, Feng Xu, Haizhou Wang, +3

EBioMedicine

Histone ModificationsSystems BiologyEpigenetic ChangeDna MethylationPan-cancer Characterization +9