Alejandro Díaz‐Holguín

AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine–associated receptor 1

Alejandro Díaz‐Holguín, Marcus Saarinen, Duc Duy Vo et al. · Science Advances · 2024 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Exploring the Effect of Halogenation in a Series of Potent and Selective A_2B Adenosine Receptor Antagonists

Rubén Prieto‐Díaz, Manuel A. González‐Gómez, Hugo Fojo-Carballo et al. · Journal of Medicinal Chemistry · 2022 · 16 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists

Alejandro Díaz‐Holguín, Azam Rashidian, Dirk Pijnenburg et al. · ChemMedChem · 2022 · 13 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A₁ Antagonists

Cristina Val, Carlos Rodríguez-García, Rubén Prieto‐Díaz et al. · Journal of Medicinal Chemistry · 2022 · 12 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14