Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging

Jin Zhou, Shu Yun Chong, Andrea Lim, +4

Aging

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

Daniel A. Kuppers, Sonali Arora, Yiting Lim, +11

Nature Communications

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity

Andrea Lim, Jin Zhou, Rohit A. Sinha, +6

Biochemical and Biophysical Research Communications

Metabolic SyndromeHepatologyBiochemistryMedicineLiver Physiology +9

Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa)

Benjamin L. Farah, Rohit A. Sinha, Yajun Wu, +7

Scientific Reports

A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia

Jin Zhou, Lauren R. Waskowicz, Andrea Lim, +7

Thyroid

Bezafibrate induces autophagy and improves hepatic lipid metabolism in glycogen storage disease type Ia

Lauren R. Waskowicz, Jin Zhou, Dustin J. Landau, +11

Human Molecular Genetics

Bezafibrate InducesPathologyFatty Liver DiseaseInsulin SignalingMetabolic Syndrome +22

<i>MED1</i> mediator subunit is a key regulator of hepatic autophagy and lipid metabolism

Jin Zhou, Brijesh Kumar Singh, Jia Pei Ho, +5

Autophagy

A fluorescent methylation-switchable probe for highly sensitive analysis of FTO<i>N</i>⁶-methyladenosine demethylase activity in cells

Adeline Cheong, Joanne J. A. Low, Andrea Lim, +2

Chemical Science

Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo

Jin Zhou, Benjamin Ng, Nicole S. J. Ko, +11

Human Molecular Genetics

MitophagyHeart FailureMitochondrial DysfunctionCellular PhysiologyCell Autophagy +15

Thyroid Hormone Receptor α Regulates Autophagy, Mitochondrial Biogenesis, and Fatty Acid Use in Skeletal Muscle

Jin Zhou, Karine Gauthier, Jia Pei Ho, +6

Endocrinology