Johannes W. Bigenzahn

Gene essentiality and synthetic lethality in haploid human cells

Vincent A. Blomen, Peter Májek, Lucas T. Jae et al. · Science · 2015 · 907 citations

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Manuele Rebsamen, Lorena Pochini, Taras Stasyk et al. · Nature · 2015 · 646 citations · Full text

Lysosomal Amino Acid, Protein Function, Signal Transduction +8

LZTR1 is a regulator of RAS ubiquitination and signaling

Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig et al. · Science · 2018 · 224 citations · Full text

TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9

Leonhard X. Heinz, JangEun Lee, Utkarsh Kapoor et al. · Nature · 2020 · 213 citations · Full text

Irf5 Activation, Molecular Biology, Systems Biology

A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis

Astrid Fauster, Manuele Rebsamen, K. Huber et al. · Cell Death and Disease · 2015 · 182 citations · Full text