Ran Guan

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Cherrie K. Donawho, Yan Luo, Yanping Luo et al. · Clinical Cancer Research · 2007 · 773 citations · Full text

Medicine, Oncology, Pharmacology +15

Potent and selective inhibitors of Akt kinases slow the progress of tumors <i>in vivo</i>

Yan Luo, Alexander R. Shoemaker, Xuesong Liu et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

Medicine, Oncology, Pharmacology +15

Small Interfering RNA–Mediated Polo-Like Kinase 1 Depletion Preferentially Reduces the Survival of p53-Defective, Oncogenic Transformed Cells and Inhibits Tumor Growth in Animals

Ran Guan, Paul Tapang, Daniel Albert et al. · Cancer Research · 2005 · 146 citations

Life Sciences, Cancer Biology, Genetics +17

Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis

Yue Zhang, Ran Guan, Jing Jiang et al. · Journal of Biological Chemistry · 2001 · 94 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Discovery of 3<i>H</i>-Benzo[4,5]thieno[3,2-<i>d</i>]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM) Kinases

Zhi‐Fu Tao, Lisa Hasvold, Joel D. Leverson et al. · Journal of Medicinal Chemistry · 2009 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10