The NK Receptor NKp30 Mediates Direct Fungal Recognition and Killing and Is Diminished in NK Cells from HIV-Infected Patients

Shu Shun Li, Stephen K. Kyei, Martina Timm-McCann, +10

Cell Host & Microbe

Primary ImmunodeficiencyIs DiminishedMedicineHuman RetrovirusImmunology +8

<i>Cryptococcus gattii</i> Is Killed by Dendritic Cells, but Evades Adaptive Immunity by Failing To Induce Dendritic Cell Maturation

Shaunna M. Huston, Shu Shun Li, Danuta Stack, +7

The Journal of Immunology

<i>Cryptococcus neoformans</i>Directly Stimulates Perforin Production and Rearms NK Cells for Enhanced Anticryptococcal Microbicidal Activity

Kaleb J. Marr, Gareth J. Jones, Chunfu Zheng, +7

Infection and Immunity

An Acidic Microenvironment Increases NK Cell Killing of Cryptococcus neoformans and Cryptococcus gattii by Enhancing Perforin Degranulation

Anowara Islam, Shu Shun Li, Paul Oykhman, +6

PLoS Pathogens

Tumor BiologyMicrobial PathogensCryptococcus GattiiMedicineImmunology +12

<i>Cryptococcus gattii</i> Capsule Blocks Surface Recognition Required for Dendritic Cell Maturation Independent of Internalization and Antigen Processing

Shaunna M. Huston, Popchai Ngamskulrungroj, Richard F. Xiang, +8

The Journal of Immunology

Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells

Paul Oykhman, Martina Timm-McCann, Richard F. Xiang, +6

Infection and Immunity

Antifungal AgentSignal TransductionNk CellPerforin-dependent KillingMedicine +12

Late Expression of Granulysin by Microbicidal CD4+ T Cells Requires PI3K- and STAT5-Dependent Expression of IL-2Rβ That Is Defective in HIV-Infected Patients

Chunfu Zheng, Gareth J. Jones, Meiqing Shi, +8

The Journal of Immunology

Granule-Dependent NK Cell Killing of Cryptococcus Requires Kinesin to Reposition the Cytolytic Machinery for Directed Cytotoxicity

Henry Ogbomo, Martina Timm-McCann, Tavish Barnes, +8

Cell Reports

Microbial PathogensImmunologyNk CellsCell DeathCytoskeleton +14

<i>Cryptococcus gattii</i> pneumonia

Kerri A. Johannson, Shaunna M. Huston, Christopher H. Mody, +1

Canadian Medical Association Journal

Critical Care MedicineHealthy WomanPathogenic MicrobiologyClinical FindingMicrobial Disease +13

Ras-related C3 Botulinum Toxin Substrate (Rac) and Src Family Kinases (SFK) Are Proximal and Essential for Phosphatidylinositol 3-Kinase (PI3K) Activation in Natural Killer (NK) Cell-mediated Direct Cytotoxicity against Cryptococcus neoformans

Richard F. Xiang, Danuta Stack, Shaunna M. Huston, +4

Journal of Biological Chemistry

Natural Killer CellsPhosphatidylinositol 3-KinasePathogenesisImmunologySrc Family Kinases +6