Marcel F. Leyton-Jaimes

Loss of mouse Stmn2 function causes motor neuropathy

Irune Guerra San Juan, Leslie A. Nash, Kevin S. Smith et al. · Neuron · 2022 · 82 citations · Full text

Medicine, Neurobiology, Neuroscience +12

Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS

Marcel F. Leyton-Jaimes, Clara Benaim, Salah Abu‐Hamad et al. · Proceedings of the National Academy of Sciences · 2016 · 43 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS

Marcel F. Leyton-Jaimes, Joy Kahn, Adrian Israelson · Proceedings of the National Academy of Sciences · 2019 · 42 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Misfolded SOD1 Accumulation and Mitochondrial Association Contribute to the Selective Vulnerability of Motor Neurons in Familial ALS: Correlation to Human Disease

Salah Abu‐Hamad, Joy Kahn, Marcel F. Leyton-Jaimes et al. · ACS Chemical Neuroscience · 2017 · 31 citations

Life Sciences, Neurology, Neuroscience +17

Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS

Anna Shteinfer‐Kuzmine, Shirel Argueti-Ostrovsky, Marcel F. Leyton-Jaimes et al. · International Journal of Molecular Sciences · 2022 · 31 citations · Full text

Life Sciences, Neurology, Neuroscience +17