John G. Geisler

Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease

Varman T. Samuel, Zhenxiang Liu, Amy Wang et al. · Journal of Clinical Investigation · 2007 · 480 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance

Cheol Soo Choi, David B. Savage, Ameya Kulkarni et al. · Journal of Biological Chemistry · 2007 · 375 citations · Full text

Life Sciences, Endocrinology, Pharmacology +15

Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.

Mitchell Klebig, John E. Wilkinson, John G. Geisler et al. · Proceedings of the National Academy of Sciences · 1995 · 294 citations

Life Sciences, Genetics, Molecular Genetics +16

Targeting Foxo1 in Mice Using Antisense Oligonucleotide Improves Hepatic and Peripheral Insulin Action

Varman T. Samuel, Cheol Soo Choi, Trevor G. Phillips et al. · Diabetes · 2006 · 176 citations

Life Sciences, Biochemistry, Endocrinology +17

Identification of Diaryl Ether-Based Ligands for Estrogen-Related Receptor α as Potential Antidiabetic Agents

Raymond J. Patch, Lily L. Searle, Alexander J. Kim et al. · Journal of Medicinal Chemistry · 2011 · 139 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17