Bernhard Sperker

Elucidation of the mechanism enabling tumor selective prodrug monotherapy.

Klaus Bosslet, Rainer H. Straub, Matthias Blumrich et al. · PubMed · 1998 · 226 citations

Tumor Biology, Drug Targeting, Oncology +14

The effects of the human <i>MDR1</i> genotype on the expression of duodenal P‐glycoprotein and disposition of the probe drug talinolol

Werner Siegmund, Karen Ludwig, Peter Dazert et al. · Clinical Pharmacology & Therapeutics · 2002 · 199 citations

Expression and Localization of P-glycoprotein in Human Heart

Konrad Meissner, Bernhard Sperker, Christiane Karsten et al. · Journal of Histochemistry & Cytochemistry · 2002 · 105 citations · Full text

Expression and function of β-glucuronidase in pancreatic cancer: potential role in drug targeting

Bernhard Sperker, Ulrike Werner, Thomas E. Mürdter et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2000 · 86 citations · Full text

Drug Targeting, Pancreatic Cancer, Biochemistry +5

Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site.

Thomas E. Mürdter, Bernhard Sperker, K T Kivistö et al. · PubMed · 1997 · 73 citations

Oncology, Enhanced Uptake, Medicine +15