Peter Chang-Whan Lee

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake

Yi Gong, Joon No Lee, Peter Chang-Whan Lee et al. · Cell Metabolism · 2006 · 260 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Youngah Jo, Peter Chang-Whan Lee, Peter V. Sguigna et al. · Proceedings of the National Academy of Sciences · 2011 · 162 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy

Wei Zhang, Li Xu, Hae‐Bin Park et al. · Nature Communications · 2020 · 93 citations · Full text

Life Sciences, Immunology, Oncology +17

Indocyanine green and poly I:C containing thermo-responsive liposomes used in immune-photothermal therapy prevent cancer growth and metastasis

Li Xu, Wei Zhang, Hae‐Bin Park et al. · Journal for ImmunoTherapy of Cancer · 2019 · 86 citations · Full text

Life Sciences, Immunology, Oncology +17

Alternative Ubiquitin Activation/Conjugation Cascades Interact with N-End Rule Ubiquitin Ligases to Control Degradation of RGS Proteins

Peter Chang-Whan Lee, Mathew E. Sowa, Steven P. Gygi et al. · Molecular Cell · 2011 · 78 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13