Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing

Panagiotis Mistriotis, Emily Wisniewski, Kaustav Bera, +11

The Journal of Cell Biology

Biophysical ModelingMolecular BiologyCytoskeletonCellular PhysiologyConfinement Hinders Motility +14

Granular impact cratering by liquid drops: Understanding raindrop imprints through an analogy to asteroid strikes

Runchen Zhao, Qianyun Zhang, Hendro Tjugito, +1

Proceedings of the National Academy of Sciences

Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area

Runchen Zhao, Alexandros Afthinos, Tian Zhu, +7

Science Advances

Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis

Yuqi Zhang, Yizeng Li, Keyata N. Thompson, +13

Nature Communications

Dorsoventral polarity directs cell responses to migration track geometries

Emily Wisniewski, Panagiotis Mistriotis, Kaustav Bera, +12

Science Advances

EngineeringCytoskeletonMechanotransductionBiomedical EngineeringOptogenetics +16

Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement

Robert A. Law, Alexander Kiepas, Habben E. Desta, +11

Science Advances

Cells TuneCell AdhesionCytoskeletonCancer MetastasisCellular Physiology +17

Hydraulic resistance induces cell phenotypic transition in confinement

Runchen Zhao, Siqi Cui, Zhuoxu Ge, +4

Science Advances

Scaling of liquid-drop impact craters in wet granular media

Qianyun Zhang, Ming Gao, Runchen Zhao, +1

Physical Review E

Geotechnical EngineeringLiquid-drop Impact CratersEngineeringImpact (Mechanics)Erosion Prediction +12

Phase I and II Clinical Studies of the STING Agonist Ulevostinag with and without Pembrolizumab in Participants with Advanced or Metastatic Solid Tumors or Lymphomas

Kevin J. Harrington, Stéphane Champiat, Joshua Brody, +17

Clinical Cancer Research

Intratumoral or Subcutaneous MK-2118, a Noncyclic Dinucleotide STING Agonist, with or without Pembrolizumab, for Advanced or Metastatic Solid Tumors or Lymphomas

Jason J. Luke, Randy F. Sweis, J. Randolph Hecht, +9

Clinical Cancer Research