Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

Ilie‐Cosmin Stancu, Niels Cremers, Hannah Vanrusselt, +9

Acta Neuropathologica

Complex invasion pattern of the cerebral cortex bymicroglial cells during development of the mouse embryo

Nina Swinnen, Sophie Smolders, Ariel Ávila, +6

Glia

Sustained synchronized neuronal network activity in a human astrocyte co-culture system

Jacobine Kuijlaars, Tutu Oyelami, Annick Diels, +14

Scientific Reports

Neurogenic Maturation of Human Dental Pulp Stem Cells Following Neurosphere Generation Induces Morphological and Electrophysiological Characteristics of Functional Neurons

Pascal Gervois, Tom Struys, Petra Hilkens, +6

Stem Cells and Development

Nondifferentiated HdpscsHdpsc CultureAdult Stem CellCerebral OrganoidBiomedical Engineering +22

Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor

Bert Brône, Pieter J. Peeters, Roger Marrannes, +4

Toxicology and Applied Pharmacology

Molecular PharmacologyMolecular PhysiologySignal TransductionG Protein-coupled ReceptorTear Gasses Cn +8

Analogues of Morphanthridine and the Tear Gas Dibenz[<i>b</i>,<i>f</i>][1,4]oxazepine (CR) as Extremely Potent Activators of the Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channel

Harrie J. M. Gijsen, Didier Berthelot, Mirko Zaja, +3

Journal of Medicinal Chemistry

Drug TargetPharmacotherapyExperimental PharmacologyPharmaceutical ChemistryMolecular Pharmacology +17

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Aviel Even, Giovanni Morelli, Loïc Broix, +17

Science Advances

Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo

Silke Smolders, Sophie Smolders, Nina Swinnen, +4

Frontiers in Cellular Neuroscience

Brain DevelopmentImmunologyMicroglial Cell ActivationNeuroinflammationInflammation +15

Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists

Harrie J. M. Gijsen, Didier Berthelot, Michel A.J. De Cleyn, +3

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryBiochemistryPotent Trpa1 AntagonistsMedicine +7

Microglial derived extracellular vesicles activate autophagy and mediate multi‐target signaling to maintain cellular homeostasis

Bram Van den Broek, Isabel Pintelon, Ibrahim Hamad, +11

Journal of Extracellular Vesicles