Sarah R. Needham

Affimer proteins are versatile and renewable affinity reagents

Christian Tiede, R. Bedford, Sophie J. Heseltine et al. · eLife · 2017 · 203 citations · Full text

Immunocytochemical Technique, Protein Assembly, Molecular Biology +16

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

Sarah R. Needham, Selene K. Roberts, Anton Arkhipov et al. · Nature Communications · 2016 · 199 citations · Full text

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

Laura C. Zanetti-Domingues, Dimitris Korovesis, Sarah R. Needham et al. · Nature Communications · 2018 · 91 citations · Full text

Single-Molecule Imaging and Fluorescence Lifetime Imaging Microscopy Show Different Structures for High- and Low-Affinity Epidermal Growth Factor Receptors in A431 Cells

S Webb, Selene K. Roberts, Sarah R. Needham et al. · Biophysical Journal · 2007 · 82 citations · Full text

Signal Transduction, Single-molecule Imaging, Molecular Imaging +10

Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution

Lin Wang, Benji Bateman, Laura C. Zanetti-Domingues et al. · Communications Biology · 2019 · 64 citations · Full text