Ariele Viacava Follis

Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects

Christina Schindler, Hannah M. Baumann, Andreas Blum et al. · Journal of Chemical Information and Modeling · 2020 · 311 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc

Dalia I. Hammoudeh, Ariele Viacava Follis, Edward V. Prochownik et al. · Journal of the American Chemical Society · 2009 · 232 citations

Life Sciences, Molecular Biology, Oncology +17

Improved low molecular weight Myc-Max inhibitors

Huabo Wang, Dalia I. Hammoudeh, Ariele Viacava Follis et al. · Molecular Cancer Therapeutics · 2007 · 187 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17

Structural Rationale for the Coupled Binding and Unfolding of the c-Myc Oncoprotein by Small Molecules

Ariele Viacava Follis, Dalia I. Hammoudeh, Huabo Wang et al. · Chemistry & Biology · 2008 · 185 citations

Life Sciences, Biochemistry, Molecular Biology +12

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

Ariele Viacava Follis, Jerry E. Chipuk, John C. Fisher et al. · Nature Chemical Biology · 2013 · 183 citations

Life Sciences, Cell Biology, Molecular Biology +15