C.G. Castles

A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions.

Suzanne A.W. Fuqua, C Wiltschke, Q. X. ZHANG et al. · PubMed · 2000 · 234 citations

Premalignant Breast Lesions, Systems Biology, Breast Cancer Evolution +11

Expression of a constitutively active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line.

C.G. Castles, Suzanne A.W. Fuqua, Diane M. Klotz et al. · PubMed · 1993 · 132 citations

Transcriptional Regulation, Deletion Variant, Breast Oncology +13

Auto-regulation of the estrogen receptor promoter

C.G. Castles, Steffi Oesterreich, Rhonda K. Hansen et al. · The Journal of Steroid Biochemistry and Molecular Biology · 1997 · 80 citations

Estrogen Receptor Promoter, Systems Biology, Signal Transduction +6

Differential Expression of Wild-Type and Variant ER mRNAs by Stocks of MCF-7 Breast Cancer Cells May Account for Differences in Estrogen Responsiveness

Diane M. Klotz, C.G. Castles, Suzanne A.W. Fuqua et al. · Biochemical and Biophysical Research Communications · 1995 · 43 citations

Breast Oncology, Differential Expression, Hormonal Receptor +9

A role for estrogen-receptor variants in endocrine resistance

Suzanne A.W. Fuqua, C Wiltschke, C.G. Castles et al. · Endocrine Related Cancer · 1995 · 32 citations

Endocrine Mechanism, Estrogen-receptor Variants, Hormonal Receptor +4