Silke Vortherms

Synthesis and Structure–Activity Relationships of Lapacho Analogues. 1. Suppression of Human Keratinocyte Hyperproliferation by 2-Substituted Naphtho[2,3-<i>b</i>]furan-4,9-diones, Activation by Enzymatic One- and Two-Electron Reduction, and Intracellular Generation of Superoxide

Alexandra Reichstein, Silke Vortherms, Sven Bannwitz et al. · Journal of Medicinal Chemistry · 2012 · 80 citations

Life Sciences, Medicinal Chemistry, Pharmacology +14

Synthesis and Structure–Activity Relationships of Lapacho Analogues. 2. Modification of the Basic Naphtho[2,3-<i>b</i>]furan-4,9-dione, Redox Activation, and Suppression of Human Keratinocyte Hyperproliferation by 8-Hydroxynaphtho[2,3-<i>b</i>]thiophene-4,9-diones

Sven Bannwitz, Dirk Krane, Silke Vortherms et al. · Journal of Medicinal Chemistry · 2014 · 41 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Oxadiazole-substituted naphtho[2,3- b ]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure−activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent

Atila Basoglu, Simone Dirkmann, Nader Zahedi Golpayegani et al. · European Journal of Medicinal Chemistry · 2017 · 16 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

8-Halo-substituted naphtho[2,3-b]thiophene-4,9-diones as redox-active inhibitors of keratinocyte hyperproliferation with reduced membrane-damaging properties

Cathrin Lindenschmidt, Dirk Krane, Silke Vortherms et al. · European Journal of Medicinal Chemistry · 2016 · 15 citations

Life Sciences, Biochemistry, Chemical Biology +15