Alanna M. Harden

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

S Ziemin-van der Poel, Norah R. McCabe, Heidi J. Gill et al. · Proceedings of the National Academy of Sciences · 1991 · 594 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)

Olatoyosi M. Sobulo, Julian Borrow, Shalini C. Reshmi et al. · Proceedings of the National Academy of Sciences · 1997 · 325 citations

Life Sciences, Genetics, Oncology +17

11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene.

Nancy J. Zeleznik‐Le, Alanna M. Harden, Janet D. Rowley · Proceedings of the National Academy of Sciences · 1994 · 234 citations

Life Sciences, Genetics, Molecular Genetics +15

Deletions of Interferon Genes in Acute Lymphoblastic Leukemia

Manuel O. Dı́az, Charles M. Rubin, Alanna M. Harden et al. · New England Journal of Medicine · 1990 · 215 citations · Full text

Life Sciences, Genetics, Molecular Genetics +9

Establishment and characterization of a megakaryoblast cell line with amplification of MLL

RJ Allen, SD Smith, RL Moldwin et al. · Leukemia · 1998 · 47 citations

Life Sciences, Cell Biology, Molecular Biology +8