Alison J. Earl

The multifunctional peptide synthetase performing the first step of penicillin biosynthesis in Penicillium chrysogenum is a 421,073 dalton protein similar to Bacillus brevis peptide antibiotic synthetases.

D. J. Smith, Alison J. Earl, G. Turner · The EMBO Journal · 1990 · 184 citations · Full text

Biosynthesis, Engineering, Biochemistry +11

Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.

D. J. Smith, Martin Burnham, John H. Bull et al. · The EMBO Journal · 1990 · 180 citations · Full text

Biosynthesis, Antimicrobial Resistance Gene, Antibiotics +8

Cloning and Heterologous Expression of the Penicillin Biosynthetic Gene Cluster from Penicillium chrysogenum

D. J. Smith, Martin Burnham, Jeffrey G. Edwards et al. · Nature Biotechnology · 1990 · 131 citations

Penicillium Chrysogenum, Biosynthesis, Engineering +10

Amplification of a Mitochondrial DNA Sequence in the Cytoplasmically Inherited ‘Ragged’ Mutant of <i>Aspergillus amstelodami</i>

Colin M. Lazarus, Alison J. Earl, Geoffrey Turner et al. · European Journal of Biochemistry · 1980 · 85 citations · Full text

Biology, Phylogenetics, Fungal Cell Biology +14

Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization

John E. Hodgson, Andrew Fosberry, Nichola S Rawlinson et al. · Gene · 1995 · 58 citations

Biosynthesis, Engineering, Biotransformation +7