David M. Smith

Genetic Factors in Determining Bone Mass

David M. Smith, Walter E. Nance, Ke Won Kang et al. · Journal of Clinical Investigation · 1973 · 585 citations · Full text

Bone Disease, Body Composition, Orthopaedic Surgery +14

Docking of the Proteasomal ATPases' Carboxyl Termini in the 20S Proteasome's α Ring Opens the Gate for Substrate Entry

David M. Smith, Shih‐Chung Chang, Soyeon Park et al. · Molecular Cell · 2007 · 526 citations · Full text

Substrate Entry, Carboxyl Termini, Cellular Enzymology +11

Ester Bond-containing Tea Polyphenols Potently Inhibit Proteasome Activity in Vitro and in Vivo

Sangkil Nam, David M. Smith, Q. Ping Dou · Journal of Biological Chemistry · 2001 · 507 citations · Full text

Mechanism of Gate Opening in the 20S Proteasome by the Proteasomal ATPases

Julius Rabl, David M. Smith, Yadong Yu et al. · Molecular Cell · 2008 · 383 citations · Full text

Gate Opening, Protein Secretion, Protein Function +13

A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomers

Tiffany A. Thibaudeau, Raymond T. Anderson, David M. Smith · Nature Communications · 2018 · 352 citations · Full text