Severe growth defect in mouse cells lacking the telomerase RNA component

Hiroyuki Niida, Takehisa Matsumoto, Hideo Satoh, +4

Nature Genetics

Genome InstabilityMouse CellsGeneticsTelomerase Rna ComponentCellular Senescence +4

Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein – Barr virus

Hidetoshi Tahara, Yoshiki Tokutake, Shizuko Maeda, +9

Oncogene

Lymphoid NeoplasiaPathogenesisImmunologyPathologyVirology +6

Extra-Chromosomal Telomere Repeat DNA in Telomerase-Negative Immortalized Cell Lines

Yoshiki Tokutake, Takehisa Matsumoto, Taro Watanabe, +7

Biochemical and Biophysical Research Communications

ChromatinGenome InstabilityGeneticsDna ReplicationChromosomal Rearrangement +2

Mutation and haplotype analyses of the Werner's syndrome gene based on its genomic structure: genetic epidemiology in the Japanese population

Takehisa Matsumoto, Osamu Imamura, Yukako Yamabe, +17

Human Genetics

Syndrome GeneMendelian DisorderGenetic DisorderGeneticsGenetic Epidemiology +7

Detection by Epitope-defined Monoclonal Antibodies of Werner DNA Helicases in the Nucleoplasm and Their Upregulation by Cell Transformation and Immortalization

Miwa Shiratori, Sakae Sakamoto, Noriyuki Suzuki, +7

The Journal of Cell Biology

Dna AnalysisMolecular BiologyPathologyImmunophenotypingEpitope-defined Monoclonal Antibodies +19

Analysis of helicase gene mutations in Japanese Werner's syndrome patients

Makaoto Goto, Osamu Imamura, Junro Kuromitsu, +9

Human Genetics

Mendelian DisorderJapanese WernerNatural SciencesGeneticsGenetic Disorder +6

Inhibition of proliferation of human immunodeficiency virus type 1 by novel heteropolyoxotungstates in vitro

Yukinori Take, Yoshiki Tokutake, Yoshio Inouye, +4

Antiviral Research

Medicinal ChemistryNovel HeteropolyoxotungstatesMedicineDrug DiscoveryHuman Retrovirus +6

In vitro antiviral activity of polyoxomolybdates. Mechanism of inhibitory effect of PM-104 (NH4)12H2(Eu4(MoO4(H2O)16(Mo7O24)4) · 13H2O on human immunodeficiency virus type 1

Yoshio Inouye, Yoshiki Tokutake, Tetsuya Yoshida, +7

Antiviral Research

Medicinal ChemistryVitro Antiviral ActivityBiochemistryMedicineNatural Sciences +8

A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs.

Akira Shimamoto, Saori Kitao, K. Ichikawa, +13

Proceedings of the National Academy of Sciences

Human Chromosome 8P11-12GeneticsGenomic MechanismMolecular BiologyMolecular Genetics +16

Inhibition of replication of human immunodeficiency virus by a heteropolyoxotungstate (PM-19).

Yoshio Inouye, Yukinori Take, Yoshiki Tokutake, +3

Chemical and Pharmaceutical Bulletin