Niels Hagenaars

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: Nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen

Bram Slütter, Suzanne M. Bal, Chantal Keijzer et al. · Vaccine · 2010 · 197 citations

Nanoparticles, Vaccination, Nanomedicine +12

Head-to-head comparison of four nonadjuvanted inactivated cell culture-derived influenza vaccines: Effect of composition, spatial organization and immunization route on the immunogenicity in a murine challenge model

Niels Hagenaars, Enrico Mastrobattista, Harrie L. Glansbeek et al. · Vaccine · 2008 · 76 citations

Vaccination, Cross-protection, Vaccine Development +10

Role of trimethylated chitosan (TMC) in nasal residence time, local distribution and toxicity of an intranasal influenza vaccine

Niels Hagenaars, Marta Mania, Pascal de Jong et al. · Journal of Controlled Release · 2010 · 64 citations

Vaccination, Mucosal Vaccination, Vaccine Development +10

Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine

Niels Hagenaars, Rolf J. Verheul, Imke Mooren et al. · Journal of Controlled Release · 2009 · 57 citations

Vaccination, Nasal Influenza Vaccine, Cross-protection +10

Physicochemical and Immunological Characterization of N,N,N-Trimethyl Chitosan-Coated Whole Inactivated Influenza Virus Vaccine for Intranasal Administration

Niels Hagenaars, Enrico Mastrobattista, Rolf J. Verheul et al. · Pharmaceutical Research · 2009 · 53 citations · Full text

Vaccination, Intranasal Administration, Mucosal Vaccination +10