Guoshun Luo

Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo

Guoshun Luo, Zhenbang Li, Xin Lin et al. · Acta Pharmaceutica Sinica B · 2020 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Targeting of the FOXM1 Oncoprotein by E3 Ligase-Assisted Degradation

Guoshun Luo, Xin Lin, Antonio Vega-Medina et al. · Journal of Medicinal Chemistry · 2021 · 49 citations · Full text

Medicine, Molecular Biology, Oncology +13

Design, synthesis and biological evaluation of novel 3-substituted 4-anilino-coumarin derivatives as antitumor agents

Guoshun Luo, Moses Muyaba, Weiting Lyu et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 42 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents

Zhichao Tang, Cheng-Zhe Wu, Tianlin Wang et al. · European Journal of Medicinal Chemistry · 2016 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Novel SERMs based on 3-aryl-4-aryloxy-2H-chromen-2-one skeleton - A possible way to dual ERα/VEGFR-2 ligands for treatment of breast cancer

Guoshun Luo, Xinyu Li, Guoqing Zhang et al. · European Journal of Medicinal Chemistry · 2017 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17