Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

Bei Zhang, Gino Salituro, Deborah Szalkowski, +15

Science

Insulin ReceptorInsulin SignalingCell Surface ReceptorInsulin-like Growth FactorAntidiabetic Activity +14

Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3

Li Huang, Annie Zhao, Jane-L. Lew, +9

Journal of Biological Chemistry

Guggulsterone Is a Farnesoid X Receptor Antagonist in Coactivator Association Assays but Acts to Enhance Transcription of Bile Salt Export Pump

Jisong Cui, Li Huang, Annie Zhao, +7

Journal of Biological Chemistry

Attenuating pregnane X receptor (PXR) activation: A molecular modelling approach

Yuzhang Gao, Steven H. Olson, James M. Balkovec, +8

Xenobiotica

Drug TargetHuman PxrReproductive HealthChemical BiologyPxr Activation +14

Auranofin efficacy against MDR<i>Streptococcus pneumoniae</i>and<i>Staphylococcus aureus</i>infections

Leire Aguinagalde, Roberto Díez‐Martínez, José Yuste, +10

Journal of Antimicrobial Chemotherapy

Novel illudins from Coprinopsis episcopalis (syn. Coprinus episcopalis), and the distribution of illudin-like compounds among filamentous fungi

Antonio González del Val, Gonzalo Platas, F. Arenal, +9

Mycological Research

BiologyIlludin-like CompoundsBioorganic ChemistryFilamentous FungiNatural Sciences +5

Inhibitors of farnesylation of Ras from a microbial natural products screening program

Dolores Vilella, M.P. Anguita Snchez, Gonzalo Platas, +11

Journal of Industrial Microbiology & Biotechnology

In Vitro Antitumor Structure–Activity Relationships of <i>threo/trans/threo/trans/erythro</i> bis-Tetrahydrofuranic Acetogenins: Correlations With Their Inhibition of Mitochondrial Complex I

José R. Tormo, Nuria DePedro, Inmaculada Royo, +6

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

Chemoprevention StrategyAnnonaceous AcetogeninsChemical BiologyPharmaceutical ChemistryTumor Biology +15

N′,2-Diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists

Jason Elliott, Robert W. Carling, Mark S. Chambers, +14

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicineImmunologyPharmacological AgentPharmacotherapy +3

Long thoracic nerve injury in breast cancer patients treated with axillary lymph node dissection

R. Belmonte, Sandra Monleón, Neus Bofill, +3

Supportive Care in Cancer

Thoracic Nerve InjuryBreast Cancer PatientsThoracic SurgeryBreast CancerSurgery +3