Shigehito Osawa

Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors

Anjaneyulu Dirisala, Kensuke Osada, Qixian Chen et al. · Biomaterials · 2014 · 76 citations

Cell-based Drug Delivery, Nanomedicine, Systemic Gene Therapy +9

Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability

Anjaneyulu Dirisala, Satoshi Uchida, Theofilus A. Tockary et al. · Journal of drug targeting · 2018 · 74 citations

Ethylene Glycol, Engineering, Molecular Biology +17

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines

Anjaneyulu Dirisala, Satoshi Uchida, Kazuko Toh et al. · Science Advances · 2020 · 73 citations · Full text

Polyplex Micelles with Double-Protective Compartments of Hydrophilic Shell and Thermoswitchable Palisade of Poly(oxazoline)-Based Block Copolymers for Promoted Gene Transfection

Shigehito Osawa, Kensuke Osada, Shigehiro Hiki et al. · Biomacromolecules · 2015 · 65 citations

Engineering, Smart Polymer, Polymer-drug Conjugate +13

Interpenetrating Polymer Network Hydrogels via a One-Pot and in Situ Gelation System Based on Peptide Self-Assembly and Orthogonal Cross-Linking for Tissue Regeneration

Shohei Ishikawa, Kazutoshi Iijima, Daisuke Matsukuma et al. · Chemistry of Materials · 2020 · 60 citations

Tissue Engineering, Situ Gelation System, Engineering +22