Jason H. Yang

Antibiotics induce redox-related physiological alterations as part of their lethality

Daniel J. Dwyer, Peter Belenky, Jason H. Yang et al. · Proceedings of the National Academy of Sciences · 2014 · 915 citations · Full text

Antibiotic efficacy is linked to bacterial cellular respiration

Michael A. Lobritz, Peter Belenky, Caroline Porter et al. · Proceedings of the National Academy of Sciences · 2015 · 751 citations · Full text

Antimicrobial Chemotherapy, Metabolic Model, Drug Resistance +18

Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control

Sylvain Meylan, Caroline Porter, Jason H. Yang et al. · Cell chemical biology · 2017 · 363 citations · Full text

Antimicrobial Susceptibility, Antibiotics, Environmental Microbiology +9

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

Allison J. Lopatkin, Sarah C. Bening, Abigail L. Manson et al. · Science · 2021 · 335 citations · Full text

A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action

Jason H. Yang, Sarah N. Wright, Meagan Hamblin et al. · Cell · 2019 · 321 citations · Full text

Antimicrobial Susceptibility, Machine Learning, Antibiotics +8