D. Holzle

From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells

Irina N. Gaisina, Franck Gallier, Andrei V. Ougolkov et al. · Journal of Medicinal Chemistry · 2009 · 127 citations · Full text

Medicine, Oncology, Pharmacology +15

Design, Synthesis, Docking, and Biological Evaluation of Novel Diazide-Containing Isoxazole- and Pyrazole-Based Histone Deacetylase Probes

Raghupathi Neelarapu, D. Holzle, Subash Velaparthi et al. · Journal of Medicinal Chemistry · 2011 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Crystal Structures of Δ1-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes

B. Nocek, Changsoo Chang, H. Li et al. · Journal of Molecular Biology · 2005 · 51 citations · Full text

Life Sciences, Biochemistry, Microbiology +6

Binding Ensemble Profiling with Photoaffinity Labeling (BEProFL) Approach: Mapping the Binding Poses of HDAC8 Inhibitors

He Bai, Subash Velaparthi, Gilles Pieffet et al. · Journal of Medicinal Chemistry · 2009 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis

Youngchang Kim, H. Li, T.A. Binkowski et al. · Journal of Structural and Functional Genomics · 2008 · 22 citations · Full text

Life Sciences, Biochemistry, Microbiology +14