T. A. Alsenani

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Active since

2022

Affiliations

University School(Current)

Case Western Reserve University

Louis Stokes Cleveland VA Medical Center

T. A. Alsenani is an author at University School specializing in antibiotic resistance mechanisms, beta-lactamase inhibitor resistance, and multidrug resistance.

Publications per year

2022–2023

Publications

Structural Characterization of the D179N and D179Y Variants of KPC-2 β-Lactamase: Ω-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam

T. A. Alsenani, S. L. Viviani, Vijay Kumar et al. · Antimicrobial Agents and Chemotherapy · 2022 · 62 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Exploring avibactam and relebactam inhibition of <i>Klebsiella pneumoniae</i> carbapenemase D179N variant: role of the Ω loop-held deacylation water

T. A. Alsenani, S. L. Viviani, Krisztina M. Papp‐Wallace et al. · Antimicrobial Agents and Chemotherapy · 2023 · 11 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses

T. A. Alsenani, M.M. Rodríguez, Bárbara Ghiglione et al. · Antimicrobial Agents and Chemotherapy · 2023 · 10 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

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