Genomic hallmarks of localized, non-indolent prostate cancer

Michael Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi, +65

Nature

UrologyCancer GenomicsProstatic DiseaseMedicineNon-indolent Prostate Cancer +1

The Proteogenomic Landscape of Curable Prostate Cancer

Ankit Sinha, Vincent Huang, Julie Livingstone, +25

Cancer Cell

UrologyGenitourinary CancerMedicineCurable Prostate CancerProstatic Disease +2

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

Satoshi Inoue, Wanda Y. Li, Alan Tseng, +35

Cancer Cell

Genome InstabilityDna DamageAlters Dna RepairNatural SciencesGenetics +8

TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer

Ken J. Kron, Alexander Murison, Stanley Zhou, +8

Nature Genetics

Transcriptional RegulationSignaling PathwayCell RegulationMedicineReceptor Tyrosine Kinase +8

Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort

Dominique Trudel, Michelle R. Downes, Jenna Sykes, +3

European Journal of Cancer

Contemporary CohortUrologySurgical OncologyPrognostic ImpactGenitourinary Cancer +5

Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer

Swneke D. Bailey, Kinjal Desai, Ken J. Kron, +16

Nature Genetics

Breast OncologySomatic VariantEsr1 ExpressionTumor HeterogeneityGenetics +9

Association of tissue promoter methylation levels of <i>APC</i>, <i>TGFβ2</i>, <i>HOXD3</i> and <i>RASSF1A</i> with prostate cancer progression

Liyang Liu, Ken J. Kron, Vaijayanti Pethe, +8

International Journal of Cancer

Epigenetic ChangePathologyEpigeneticsTumor BiologyTranscriptional Regulation +16

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

Frann Antignano, Kyle Burrows, Michael R. Hughes, +16

Journal of Clinical Investigation

T-regulatory CellImmunologyImmune RegulationRegulatory T CellsCd4 T Cell Responses +19

The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization

Naoya Takayama, Alex Murison, Shin‐ichiro Takayanagi, +20

Cell stem cell

ChromatinLineage PlasticityEmbryonic Stem CellDevelopmental BiologyCell Division +9

Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays

Ken J. Kron, Vaijayanti Pethe, Laurent Briollais, +8

PLoS ONE