Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration

Poh-Shiow Yeh, Weu Wang, Ya-An Chang, +3

Cancer Letters

Cell AutophagyMitophagySignal TransductionDevelopmental BiologySignaling Pathway +10

The epigenetic effects of amyloid-β1–40 on global DNA and neprilysin genes in murine cerebral endothelial cells

Kun-Lin Chen, Steven Sheng-Shih Wang, Yi‐Yuan Yang, +3

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineEpigenetic EffectsNeprilysin Genes +8

Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway

Chien‐Ju Lin, Ta-Liang Chen, Yuan‐Yun Tseng, +4

Toxicology and Applied Pharmacology

Cell AutophagyMitophagyGliomaApoptosisAutophagy +9

MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells

Chung- Ching Chio, Jia‐Wei Lin, Heien An Cheng, +5

Archives of Toxicology

Hypoxia-induced ApoptosisMedicineApoptosisImmunologyCell Death +8

Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation

Gone-Jhe Wu, Ta-Liang Chen, Yune‐Fang Ueng, +1

Toxicology and Applied Pharmacology

InflammationToll-like ReceptorsCytokineInterleukin-6 Gene ExpressionsAnti-inflammatory +12

Propofol Suppresses Macrophage Functions and Modulates Mitochondrial Membrane Potential and Cellular Adenosine Triphosphate Synthesis

Ruei‐Ming Chen, Chih‐Hsiung Wu, Huai-Chia Chang, +4

Anesthesiology

Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma

Wen‐Bin Yang, Che-Chia Hsu, Tsung‐I Hsu, +10

Neuro-Oncology

Lipopolysaccharide triggers macrophage activation of inflammatory cytokine expression, chemotaxis, phagocytosis, and oxidative ability via a toll-like receptor 4-dependent pathway: Validated by RNA interference

Tsu-Tuan Wu, Ta-Liang Chen, Ruei‐Ming Chen

Toxicology Letters

InflammationToll-like ReceptorsInflammatory Cytokine ExpressionAutoimmune DiseaseRna Interference +9

Suppressive effects of ketamine on macrophage functions

Yi Chang, Ta-Liang Chen, Joen‐Rong Sheu, +1

Toxicology and Applied Pharmacology

Macrophage BiologyInflammationCytokineAnti-inflammatoryMolecular Physiology +5

Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice

Ching-Hao Li, Ming‐Kwang Shyu, Cheng Jhan, +6

Toxicological Sciences

NanoparticlesNanotherapeuticsEngineeringBbb PermeabilityBiomedical Engineering +23