J.J.J. van Giezen

Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP‐induced receptor signaling and platelet aggregation

J.J.J. van Giezen, Lena Nilsson, P. Berntsson et al. · Journal of Thrombosis and Haemostasis · 2009 · 279 citations

Medicine, Molecular Biology, Pharmacology +16

Characterization of the Adenosine Pharmacology of Ticagrelor Reveals Therapeutically Relevant Inhibition of Equilibrative Nucleoside Transporter 1

Duncan Armstrong, Claire Summers, Lorna Ewart et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 2014 · 240 citations

Medicine, Pharmacology, Pharmacotherapy +12

Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans

Ann Wittfeldt, Håkan Emanuelsson, Gunnar Brandrup‐Wognsen et al. · Journal of the American College of Cardiology · 2013 · 196 citations

Medicine, Cardiology, Pharmacology +10

Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

J.J.J. van Giezen, James E. Sidaway, Philip Glaves et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 2011 · 193 citations

Medicine, Cardiology, Pharmacology +12

Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

J.J.J. van Giezen, Pia Berntsson, Helen Zachrisson et al. · Thrombosis Research · 2009 · 78 citations

Medicine, Hematology, Pharmacology +15