J.J.J. van Giezen

Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP‐induced receptor signaling and platelet aggregation

J.J.J. van Giezen, Lena Nilsson, P. Berntsson et al. · Journal of Thrombosis and Haemostasis · 2009 · 277 citations

Molecular Pharmacology, Signal Transduction, Blood Platelet +11

Characterization of the Adenosine Pharmacology of Ticagrelor Reveals Therapeutically Relevant Inhibition of Equilibrative Nucleoside Transporter 1

Duncan Armstrong, Claire Summers, Lorna Ewart et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 2014 · 238 citations

Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans

Ann Wittfeldt, Håkan Emanuelsson, Gunnar Brandrup‐Wognsen et al. · Journal of the American College of Cardiology · 2013 · 194 citations

Molecular Pharmacology, Thrombosis, Cardiovascular Disease +8

Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

J.J.J. van Giezen, James E. Sidaway, Philip Glaves et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 2011 · 192 citations

Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

J.J.J. van Giezen, Pia Berntsson, Helen Zachrisson et al. · Thrombosis Research · 2009 · 78 citations

Thrombosis, Bleeding Effects, Blood Platelet +10