Cristina S. J. Rocha

An oral antisense oligonucleotide for PCSK9 inhibition

Peter Gennemark, Katrin Walter, Niclas Clemmensen et al. · Science Translational Medicine · 2021 · 121 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

Pedro M. D. Moreno, Sylvain Geny, Y. Vladimir Pabon et al. · Nucleic Acids Research · 2013 · 30 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16

Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity

Osama Saher, Cristina S. J. Rocha, Eman M. Zaghloul et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2018 · 21 citations · Full text

Pharmacy, Biochemistry, Molecular Pharmaceutics +14

RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form

Cristina S. J. Rocha, Oscar P. B. Wiklander, Lilian Larsson et al. · Journal of Molecular and Cellular Cardiology · 2015 · 19 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Nuclease resistant oligonucleotides with cell penetrating properties

Stefan Milton, Dmytro Honcharenko, Cristina S. J. Rocha et al. · Chemical Communications · 2015 · 19 citations

Pharmacy, Molecular Biology, Nucleic Acid Biochemistry +15