Dominant-Negative Features of Mutant <i>TP53</i> in Germline Carriers Have Limited Impact on Cancer Outcomes

Paola Monti, Chiara Perfumo, Alessandra Bisio, +7

Molecular Cancer Research

EngineeringCancer PathologyGermline Tp53 MutationsGeneticsPathology +17

Whole-genome cartography of p53 response elements ranked on transactivation potential

Toma Tebaldi, Sara Zaccara, Federica Alessandrini, +3

BMC Genomics

The Immunoregulatory Potential of Particle Radiation in Cancer Therapy

Daniel K. Ebner, Walter Tinganelli, Alexander Helm, +5

Frontiers in Immunology

p53-directed translational control can shape and expand the universe of p53 target genes

Sara Zaccara, Toma Tebaldi, Chiara Pederiva, +3

Cell Death and Differentiation

P53-directed Translational ControlP53 Target GenesCell RegulationNatural SciencesMolecular Biology +6

Identification of new p53 target microRNAs by bioinformatics and functional analysis

Alessandra Bisio, Veronica De Sanctis, Valerio Del Vescovo, +4

BMC Cancer

Discovery of a new small-molecule inhibitor of p53–MDM2 interaction using a yeast-based approach

Clara Pereira, Alessandra Bisio, Yari Ciribilli, +8

Biochemical Pharmacology

New Small-molecule InhibitorDrug TargetP53–mdm2 InteractionMedicineSmall Molecules +10

Functional analysis of CDKN2A/p16INK4a 5′-UTR variants predisposing to melanoma

Alessandra Bisio, Sabina Nasti, Jennifer Jordan, +8

Human Molecular Genetics

Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule

Joana Soares, Liliana Raimundo, Nuno A. L. Pereira, +13

Oncotarget

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

Yari Ciribilli, Paola Monti, Alessandra Bisio, +10

Nucleic Acids Research

ChromatinTranscriptional RegulationGenome InstabilityCrystal StructureP53 Family Proteins +12

TP53 Mutants in the Tower of Babel of Cancer Progression

Alessandra Bisio, Yari Ciribilli, Gilberto Fronza, +2

Human Mutation