Geoffrey Wells

Antitumor Benzothiazoles. 26. 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a Simple Fluorinated 2-Arylbenzothiazole, Shows Potent and Selective Inhibitory Activity against Lung, Colon, and Breast Cancer Cell Lines

Catriona G. Mortimer, Geoffrey Wells, Jean-Philippe Crochard et al. · Journal of Medicinal Chemistry · 2005 · 474 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Synthesis and Biological Properties of Benzothiazole, Benzoxazole, and Chromen-4-one Analogues of the Potent Antitumor Agent 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648)

Stefania Aiello, Geoffrey Wells, Erica L. Stone et al. · Journal of Medicinal Chemistry · 2008 · 336 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism

Yuta Horie, Takafumi Suzuki, Jin Inoue et al. · Communications Biology · 2021 · 173 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy

Daniel A. East, Francesca Fagiani, James Crosby et al. · Chemistry & Biology · 2014 · 148 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction

Rowena Hancock, Hélène Bertrand, Tadayuki Tsujita et al. · Free Radical Biology and Medicine · 2011 · 145 citations

Life Sciences, Molecular Biology, Pharmacology +12