Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Susan E. Logue, Eoghan P. McGrath, Patricia A. Cleary, +16

Nature Communications

The Human Ubiquitin C Promoter Directs High Ubiquitous Expression of Transgenes in Mice

Michael Schorpp, Richard Jäger, K. Schellander, +4

Nucleic Acids Research

Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth

Richard Jennemann, Roger Sandhoff, Shijun Wang, +10

Proceedings of the National Academy of Sciences

Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice

Richard Jäger, Ute Herzer, Johannes Schenkel, +1

Oncogene

Cancer ResearchCell RegulationOncogenic AgentMedicineApoptosis +10

Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase

Nadia Munarini, Richard Jäger, Susanne Abderhalden, +6

Journal of Cell Science

Transgenic MiceMammary Gland DevelopmentTissue DevelopmentSignaling PathwayReceptor Tyrosine Kinase +15

Transcription factor AP‐2γ, a novel marker of gonocytes and seminomatous germ cell tumors

Katharina Pauls, Richard Jäger, Susanne N. Weber, +4

International Journal of Cancer

Novel MarkerImmunologyPathologyCancer BiologyTumor Biology +16

Methods for Studying ER Stress and UPR Markers in Human Cells

Donna Kennedy, Afshin Samali, Richard Jäger

Methods in molecular biology

Biomarker (Medicine)Stress HormoneStressHuman CellsPhysiology +7

Transcription factor AP-2gamma stimulates proliferation and apoptosis and impairs differentiation in a transgenic model.

Richard Jäger, Uwe Werling, Stephan Rimpf, +2

PubMed

GeneticsApoptosisCell DeathCell ProliferationImpairs Differentiation +17

Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis

Jochen Maurer, Sebastian Fuchs, Richard Jäger, +3

Differentiation

Embryonic Stem CellCell LineageDevelopmental BiologyConditional TransgenesisMedicine +9

Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo.

Kristel Schorr, Minglin Li, U. Bar-Peled, +8

PubMed

Breast OncologyApoptosisImmunologyCell DeathCell Proliferation +18