Carly Cardello

LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

Lawrence P. Andrews, Samuel C. Butler, Jian Cui et al. · Cell · 2024 · 235 citations · Full text

Life Sciences, Cancer Biology, Immunology +17

COVID-19 versus Non–COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes

William Bain, Haopu Yang, Faraaz Shah et al. · Annals of the American Thoracic Society · 2021 · 172 citations · Full text

Medicine, Infectious Diseases, Inflammation +16

Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity

Anthony R. Cillo, Carly Cardello, Feng Shan et al. · Cell · 2024 · 152 citations · Full text

Life Sciences, Cancer Biology, Immunology +16

Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study

Matthew K. Hensley, William Bain, Jana L. Jacobs et al. · Clinical Infectious Diseases · 2021 · 140 citations · Full text

Life Sciences, Immunology, Infectious Diseases +15

Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3

Stephanie Grebinoski, Qianxia Zhang, Anthony R. Cillo et al. · Nature Immunology · 2022 · 104 citations · Full text

Life Sciences, Cell Biology, Immunology +14