Mark P. Healy

Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

Andrew Barker, Keith H. Gibson, Walter Grundy et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 559 citations · Full text

Molecular Pharmacology, Drug Targeting, Oncology +10

Rhodium‐Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α‐Branched Products

Louis K. M. Chan, Darren L. Poole, Di Shen et al. · Angewandte Chemie International Edition · 2013 · 234 citations · Full text

Chemical Engineering, Engineering, Industrial Catalysis +13

Hydrogen‐Borrowing and Interrupted‐Hydrogen‐Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium

Di Shen, Darren L. Poole, Camilla C. Shotton et al. · Angewandte Chemie International Edition · 2014 · 176 citations · Full text

Engineering, Ketone Enolates, Organic Chemistry +17

Rhodium‐Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α‐Branched Products

Louis K. M. Chan, Darren L. Poole, Di Shen et al. · Angewandte Chemie · 2013 · 63 citations · Full text

Rhodium‐catalyzed Methylation, Chemical Engineering, Engineering +12

Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists

Adrian Hall, Stephen J. Atkinson, Susan H. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 42 citations · Full text

Biochemistry, Functional Selectivity, Medicine +4