Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms

Fabı́ola Traina, Valeria Visconte, Paul Elson, +15

Leukemia

Hematological MalignancyMolecular MutationsMedicineTreatment ResponseDnmt Inhibitors +5

Increased CDA Expression/Activity in Males Contributes to Decreased Cytidine Analog Half-Life and Likely Contributes to Worse Outcomes with 5-Azacytidine or Decitabine Therapy

Reda Z. Mahfouz, Ania Jankowska, Quteba Ebrahem, +13

Clinical Cancer Research

Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes

Mikkael A. Sekeres, Ramón V. Tiu, Rami S. Komrokji, +14

Blood

Ruxolitinib leads to improvement of pulmonary hypertension in patients with myelofibrosis

Ali Tabarroki, Daniel J. Lindner, Valeria Visconte, +10

Leukemia

HypertensionAntifibrotic TherapyPulmonary Arterial HypertensionPulmonary CirculationHematology +10

Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron

Valeria Visconte, Nanthawan Avishai, Reda Z. Mahfouz, +12

Leukemia

Hematological MalignancyGenetic DisorderIron MetabolismGeneticsDistinct Iron Architecture +8

Prognosis of acute renal failure in children

Hasan Otukesh, Rozita Hoseini, Majid Chalian, +2

Pediatric Nephrology

GlomerulonephritisUrologyAcute Renal FailureMedicineKidney Failure +5

Familial systemic mastocytosis with germline KIT K509I mutation is sensitive to treatment with imatinib, dasatinib and PKC412

Paula de Melo Campos, João Agostinho Machado‐Neto, Renata Scopim‐Ribeiro, +11

Leukemia Research

Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts

Valeria Visconte, Ali Tabarroki, Li Zhang, +11

Journal of Hematology & Oncology

Impact of allogeneic hematopoietic cell transplant in patients with myeloid neoplasms carrying spliceosomal mutations

Betty K. Hamilton, Valeria Visconte, Xuefei Jia, +12

American Journal of Hematology

Short-term and long-term outcome of hemolytic uremic syndrome in Iranian children

Hasan Otukesh, Rozita Hoseini, Pedram Golnari, +3

Journal of Nephrology