Xenobiotic Stress Induces Hepatomegaly and Liver Tumors via the Nuclear Receptor Constitutive Androstane Receptor

Wendong Huang, Jun Zhang, Michele N. Washington, +4

Molecular Endocrinology

PathologyCell DeathOxidative StressHepatotoxicityRadiation Oncology +17

A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets

Zhipeng Li, Ryan J. Schulze, Shaun G. Weller, +8

Science Advances

MitophagyLipid DropletsLipid MovementAutophagic DigestionCell Autophagy +14

A Novel Role for Thyroid-Stimulating Hormone: Up-Regulation of Hepatic 3-Hydroxy-3-Methyl-Glutaryl-Coenzyme A Reductase Expression Through the Cyclic Adenosine Monophosphate/Protein Kinase A/Cyclic Adenosine Monophosphate–Responsive Element Binding Protein Pathway

Limin Tian, Yongfeng Song, Mingzhao Xing, +16

Hepatology

Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia

Xiaodong Zhang, Alicia M. Saarinen, Taro Hitosugi, +4

eLife

Lipid PeroxidationMetabolic RemodelingCancer BiologyRedox BiologyTumor Biology +15

Accelerated senescence of renal tubular epithelial cells is associated with disease progression of patients with immunoglobulin A (IgA) nephropathy

Jun Liu, Yang Ju-rong, Yani He, +6

Translational research

Glomerular DiseaseDisease ProgressionImmunologyAccelerated SenescencePathology +16

PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein

S. M. Johnson, Hanmei Bao, Cailin E. McMahon, +7

Nature Communications

Association Between Lipid Levels and Major Adverse Cardiovascular Events in Rheumatoid Arthritis Compared to Non–Rheumatoid Arthritis Patients

Katherine P. Liao, Jun Liu, Bing Lü, +2

Arthritis & Rheumatology

Spinal 5-HT₇ Receptors Are Critical for Alternating Activity During Locomotion: In Vitro Neonatal and In Vivo Adult Studies Using 5-HT₇ Receptor Knockout Mice

Jun Liu, Turgay Akay, Peter B. Hedlund, +2

Journal of Neurophysiology

Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat

Yan Zhang, Jun Liu, Sha Li, +4

BMC Cardiovascular Disorders

HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia

Davide Povero, Yongbin Chen, S. M. Johnson, +13

Journal of Hepatology

BiochemistryRedox RegulatorPhysiologyHypoxia (Medicine)Metabolic Regulation +7